师资队伍
当前位置: 首页>>师资队伍>>正文

                                                   
刘薇

                                                      

  职  称: 副教授      
 电  话: 0411-84709160
 Email : liu_wei@dlut.edu.cn
 研究室: 生态毒理研究室
                                                       

                                                       

教育及工作经历                                                      

教育经历      

1998.092002.07  南京气象学院大气科学系 攻读学士学位

2002.092008.04  大连理工大学环境与生命学院  攻读博士学位

2008.04           获博士学位

       

工作简历      

2008.05至今          大连理工大学环境学院 讲师,副教授      

2012.03至今     中化集团沈阳化工研究院有限公司安全评价中心,博士后

 

学术及社会兼职

《生态毒理学报》 编委

国际毒理学会(Society of Toxicology, SOT) 会员

国际环境毒理和化学学会(Society of Environmental Toxicology and Chemistry, SETAC) 会员

中国毒理学会 会员

 

     

指导硕、博士生研究方向      

(1) 持久性有机污染物暴露评估        

(2) 污染物毒性效应和机理研究        

(3) 化学品安全性评价动物实验替代方法        

       

研究领域      

科研项目(主持和参加)      

1.        典型环境污染物对性别决定和性别稳定性干扰作用机制研究。国家自然科学基金面上项目,2013.1-2016.12

2.        水中典型污染物去除的多技术耦合联用、协同原理及安全性评价。国家自然科学基金重大项目,2016.1-2020.12

3.        污水多目标回用全过程风险与技术经济评价方法和体系。国家重点研发计划项目,2016.7-2020.6

4.        PFOS对神经突触可塑性的影响及其机理研究。国家自然科学基金面上项目,2012.1-2015.12

5.        典型全氟烷酸化合物的人类慢性暴露生物标志物研究。国家自然科学基金项目,2012.01-2014.126.        利用基因组学以人类干细胞体外检测遗传毒性效应和机制。中国博士后科学基金面上项目,2012.10-2014.3

7.        工业废水生态安全性指标体系与评价方法的构建。国家水体污染控制与治理科技重大专项子课题任务,2012.1-2015.12

8.        树叶中典型全氟烷酸化合物的富集规律、机理及环境指示作用研究。大连理工大学基本科研业务费专项项目(理科基础科研专题)2012.1-2013.12

9.        室内空气污染对健康影响评价技术研究。国家高技术研究发展计划(863计划)项目,2010.12-2013.12

10.    抗生素水环境光化学转化/光致毒性机理与计算模拟。国家自然科学基金重点项目,2012.1-2016.12

 

专著和论文

近期发表的代表性论文:

1.      Yongan Wang, Qing Yang, Wei Liu*, Mingxi Yu, Zhou Zhang, Xiaoyu Cui. Di (2-ethylhexyl) phthalate exposure in utero damages Sertoli cell differentiation via disturbance of sex determination pathway in fetal and postnatal mice. Toxicological Sciences 2016,152(1):53-61. SCI收录, IF2015=3.880

2.      Qian Zhang, Huimin Zhao, Wei Liu*, Zhou Zhang, Hui Qin, Fang Luo, Song Leng. Developmental perfluorooctane sulfonate exposure results in tau hyperphosphorylation and β-amyloid aggregation in adults rats: incidence for link to Alzheimer's disease. Toxicology 2016, 347:40-46. SCI收录, IF2015=3.817

3.      Qian Zhang, Wei Liu*, Qiao Niu, Yu Wang, Huimin Zhao*, Huifang Zhang, Jing Song, Shuji Tsuda, Norimitsu Saito. Effects of perfluorooctane sulfonate and alternatives on long term potentiation in hippocampus CA1 region of adult rats in vivo. Toxicology Research 2016, 5:539-546. SCI收录, IF2015=2.161

4.      Bei Gao, Xin He, Wei Liu*, Huanhuan Zhang, Norimitsu Saito, Shuji Tsuda. Distribution of perfluoroalkyl compounds in rats: indication for using hair as bioindicator of exposure. Journal of Exposure Science and Environmental Epidemiology 2015, 25(6):632-8. SCI收录, IF2014=3.185

5.      Yu Wang, Huimin Zhao, Qian Zhang, Wei Liu*, Xie Quan. Perfluorooctane sulfonate induces apoptosis of hippocampal neuron in rat offspring associated with calcium overload. Toxicology Research, 2015, 4:931-938. SCI收录, IF2014=3.983

6.      Huanhuan Zhang, Wei Liu*, Xin He, Yu Wang, Qian Zhang. Uptake of perfluoroalkyl acids in the leaves of coniferous and deciduous broad-leaved trees. Environmental Toxicology and Chemistry 2015, 34:1499-1504. SCI收录, IF2014=3.225

7.      Fan Wang, Wei Liu*, Faqi Wang, Junsheng Ma. Prenatal and neonatal exposure to perfluorooctane sulfonic acid results in aberrant changes in miRNA expression profile and levels in developing rat livers. Environmental Toxicology 2015, 30(6):712-23. SCI收录, IF2014=3.197

8.      Yongan Wang, Wei Liu*, Qing Yang*, Mingxi Yu, Zhou Zhang. Di (2-ethylhexyl) phthalate exposure during pregnancy disturbs temporal sex determination regulation in mice offspring. Toxicology 2015, 336:10-16. SCI收录, IF2014=3.621

9.      Mingxi Yu, Jingyun Wang, Wei Liu*, Junwen Qin, Quan Zhou, Yongan Wang, Huihui Huang, Wenli Chen, Chao Ma. Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice. Toxicology 2014, 321, 89-95. SCI收录, IF2012=4.017.

10.  Fan Wang, Chonglei Li, Wei Liu*, Yihe Jin. Potential mechanisms of neurobehavioral disturbances in mice caused by sub-chronic exposure to low-dose VOCs. Inhalation Toxicology 2014, 26(4): 250–258. SCI收录, IF2012=1.894

11.  Wei Liu, Lei Xu, Xiao Li, Yihe Jin*, Kazuaki Sasaki, Norimitsu Saito, Itaru Sato, Shuji Tsuda. Human nails analysis as biomarker of exposure to perfluoroalkyl compounds. Environmental Science & Technology 2011, 45, 8144-8150. SCI收录, EI收录. IF2011=5.228.

12.  Wei Liu, Yihe Jin*, Xie Quan, Kazuaki Sasaki, Norimitsu Saito, Shoji F. Nakayama, Itaru Sato, Shuji Tsuda. Perfluorosulfonates and perfluorocarboxylates in Snow and Rain in Dalian, China. Environment International 2009, 35(4), 737-742. SCI收录, EI收录. IF2011=5.297.

13.  Wei Liu, Yaobin Zhang, Xie Quan*, Yihe Jin, Shuo Chen. Effect of perfluorooctane sulfonate on toxicity and cell uptake of other compounds with different hydrophobicity in green alga. Chemosphere 2009, 75, 405-409. SCI收录, EI收录. IF2011=3.206.

14.  Wei Liu, Xiao Li, Lei Xu, Li Liu, Yihe Jin*. Influence of gestation, regular bleeding and intermittent exposure on blood perfluorooctane sulfonate levels in mice: potential factors inducing sex difference and affecting exposure evaluation. The Journal of Toxicological Sciences 2010, 35(3), 309-316. SCI收录, IF2011=1.522

15.  Wei Liu, Guanghui Dong, Yihe Jin*, Kazuaki Sasaki, Norimitsu Saito, Itaru Sato, Shuji Tsuda, Shoji F. Nakayama. Occurrence of perfluoroalkyl Acids in Precipitation from Shenyang, China. Chinese Science Bulletin 2009, 54(14): 2440-2445. SCI收录, IF2011=1.321.

16.  Wei Liu, Guanghui Dong, Yingwei Luo, Li Liu, Ziwei Cao, Xiaona Li, Yihe Jin*. Estimation of reference values for PFOS and PFOA in human biomonitoring and relevance of exposure among family members in China. Journal of Environmental Protection 2012, 3, 353-361.

17.  Lei Xu, Wei Liu*, Yihe Jin. Perfluorooctane sulfonate and perfluorooctanoic acid in the fingernails of urban and rural children. Chinese Science Bulletin 2010, 55(33): 3755-3762. SCI收录, IF2011=1.321.

18.  Yu Wang, Wei Liu, Qian Zhang, Huimin Zhao*, Xie Quan. Effects of developmental perfluorooctane sulfonate exposure on spatial learning and memory ability of rats and mechanism associated with synaptic plasticity. Food and Chemical Toxicology 2015, 76, 70-76. SCI收录, IF2014=2.69

19.  Mingxi Yu, Wei Liu, Jingyun Wang*, Junwen Qin, Yongan Wang, Yu Wang. Effects of tamoxifen on autosomal genes regulating ovary maintenance in adult mice. Environmental Science and Pollution Research 2015, 22(24):20234-44. SCI收录, IF2014=2.828

20.  Faqi Wang, Wei Liu, Junsheng Ma, Mingxi Yu, Yihe Jin*, Jiayin Dai. Prenatal and neonatal exposure to perfluorooctane sulfonic acid results in changes in miRNA expression profiles and synapse associated proteins in developing rat brains. Environmental Science & Technology 2012, 46(12), 6822-6829. SCI收录, EI收录. IF2011=5.228

21.  Wenjuan Zhang, Wei Liu, Jing Zhang, Huimin Zhao, Yaobin Zhang, Xie Quan, Yihe Jin*. Characterisation of acute toxicity, genotoxicity and oxidative stress posed by textile effluent on zebrafish. Journal of Environmental Sciences 2012, 24(11), 2019-2027.

22.  Jia Bao, Wei Liu, Li Liu, Yihe Jin*, Jiayin Dai, Xiaorong Ran, Zhixu Zhang, Tsuda Shuji. Perfluorinated compounds in the environment and the blood of residents living near fluorochemical plants in fuxin, China. Environmental Science & Technology 2011, 45(19), 8075-8080. SCI收录, EI收录. IF2011=5.228.

23.  Faqi Wang, Wei Liu, Yihe Jin*, Jiayin Dai, Wenguang Yu, Xiaohui Liu, Li Liu. Transcriptional Effects of Prenatal and Neonatal Exposure to PFOS in Developing Rat Brain. Environmental Science & Technology 2010, 44(5), 1847-1853. SCI收录, EI收录. IF2011=5.228.

24.  Wenguang Yu, Wei Liu, Yihe Jin*, Xiaohui Liu, Faqi Wang, Li Liu, Shoji Nakayama. Prenatal and postnatal impact of perfluorooctane sulfonate (PFOS) on rat development: A cross-foster study on chemical burden and thyroid hormone system. Environmental Science & Technology 2009, 43(21), 8416-8422. SCI收录, EI收录. IF2011=5.228.

25.  Faqi Wang, Wei Liu, Yihe Jin*, Jiayin Dai, Hongxia Zhao, Qing Xie, Xiaohui Liu, Wenguang Yu, Junsheng Ma. Interaction of PFOS and BDE-47 Co-exposure on Thyroid Hormone Levels and TH-related Gene and Protein Expression in Developing Rat Brains. Toxicological Sciences 2011, 121(2), 279-291. SCI收录. IF2011=4.652.

26.  Wenguang Yu, Wei Liu, Li Liu, Yihe Jin*. Perfluorooctane sulfonate increased hepatic expression of OAPT2 and MRP2 in rats. Archives of Toxicology 2011, 85(6), 613-621. SCI收录, IF2011=4.674.

27.  Xiaohui Liu, Wei Liu, Yihe Jin*, Wenguang Yu, Faqi Wang, Li Liu. Effect of gestational and lactational exposure to perfluorooctane sulfonate (PFOS) on calcium-dependent signaling molecules gene expression in rats' hippocampus. Archives of Toxicology 2010, 84(1), 71-79. SCI收录, IF2011=4.674.

28.  Xiaohui Liu, Wei Liu, Yihe Jin*, Wenguang Yu, Li Liu, Hongyao Yu. Effects of subchronic perfluorooctane sulfonate exposure of rats on calcium-dependent signaling molecules in the brain tissue. Archives of Toxicology 2010, 84(6), 471-479. SCI收录, IF2011=4.674.

29.  Jia Bao, Wei Liu, Li Liu, Yihe Jin, Xiaorong Ran, Zhixu Zhang. Perfluorinated compounds in urban river sediments from Guangzhou and Shanghai of China. Chemosphere 2010, 80(2), 123-130. SCI收录, EI 收录, IF2011=3.206.

30.  Yihe Jin, Wei Liu, Itaru Sato, Shoji F. Nakayama, Kazuaki Sasaki, Norimitsu Saito, Shuji Tsuda. PFOS and PFOA in environmental and tap water in China. Chemosphere 2009, 77(5), 605-611. SCI收录, EI 收录, IF2011=3.206.

31.  Wenguang Yu, Wei Liu, Yihe Jin*. Effects of perfluorooctane sulfonate on rat thyroid hormone biosynthesis and metabolism. Environmental Toxicology and Chemistry 2009, 28(5), 990-996. SCI收录, EI收录. IF2011=2.809.

32.  Jing Zhang, Yaobin Zhang, Wei Liu, Xie Quan, Shuo Chen, Huimin Zhao, Yihe Jin, Wenjuan Zhang. Evaluation of removal efficiency for acute toxicity and genotoxicity on zebrafish in anoxic-oxic process from selected municipal wastewater treatment plants. Chemosphere 2013, 90(11): 2662-2666.

33.  Fan Wang, Chonglei Li, Wei Liu, Yihe Jin*. Oxidative damage and genotoxic effect in mice caused by sub-chronic exposure to low-dose volatile organic compounds. Inhalation Toxicology 2013, 25(5): 235-42.

34.  Feng Tan, Yihe Jin, Wei Liu, Xie Quan, Jingwen Chen, Zhen Liang. Global liver proteome analysis using iTRAQ labeling quantitative proteomic technology to reveal biomarkers in mice exposed to perfluorooctane sulfonate (PFOS). Environmental Science & Technology 2012, 46(21): 12170-12177.

35.  Fan Wang, Chonglei Li, Wei Liu, Yihe Jin*. Effect of exposure to volatile organic compounds (VOCs) on airway inflammatory responses in mice. The Journal of Toxicological Sciences 2012, 37(4), 739-748. SCI收录, IF2011=1.522

36.  Fan Wang, Chonglei Li, Wei Liu, Yihe Jin. Oxidative stress levels of Kunming mice following short-term exposure to volatile organic compounds (VOCs) mixture. Journal of Animal and Veterinary Advances 2012, 11 (18): 3417-3426.

37.  Fan Wang, Chonglei Li, Wei Liu, Yihe Jin. Effects of exposure to VOCs on spatial learning and memory and the expression of NMDA receptor in mice. Journal of Animal and Veterinary Advances 2012, 11 (18): 3355-3364.

38.  Xiaohui Liu, Yihe Jin*, Wei Liu, Faqi Wang, Shuang Hao. Possible mechanism of perfluorooctane sulfonate and perfluorooctanoate on the release of calcium ion from calcium stores in primary cultures of rat hippocampal neurons. Toxicology in Vitro 2011, 25(7), 1294-1301. SCI收录,IF2011=2.775.

39.  Jia Bao, Yihe Jin, Wei Liu, Xiaorong Ran, Zhixu Zhang. Perfluorinated compounds in sediments from the Daliao river system of northeast China. Chemosphere 2009, 77(5), 652-657. SCI收录, EI 收录, IF2011=3.206.

40.  Xiao Li, Jianqing Zhang, Wei Liu, Xiaona Li, Xin Zhang, Yousheng Jiang, Jian Zhou, Yihe Jin*. Serum levels of perfluorinated compounds in the general population in Shenzhen, China. Chinese Science Bulletin 2011,56(28-29), 3092-3099. SCI收录, IF2011=1.321.

 

成果及奖励

1.         获大连理工大学2016年教学质量优良奖.

2.         获大连理工大学2014年教学质量优良奖.

3.         获大连理工大学 “考核优秀”荣誉称号,2011.

4.         获大连理工大学化工与环境生命学部 “优秀教师”荣誉称号,2011.

5.         王凡,李崇磊,刘薇,金一和Oxidative damage and genotoxic effect in mice caused by sub-chronic exposure to low-dose volatile organic compounds辽宁省自然科学学术成果奖 二等奖,2014.

6.         刘薇,许蕾,李笑,金一和。Human nails analysis as biomarker of exposure to perfluoroalkyl compounds。辽宁省自然科学学术成果奖,三等奖,2012.

7.         刘薇。Human nails analysis as biomarker of exposure to perfluoroalkyl compounds。大连市自然科学优秀学术论文,一等奖,2012.

8.         刘薇,金一和,全燮。大连市降水中全氟烷酸、羧酸化合物的污染水平和分布特征。辽宁省自然科学学术成果奖,三等奖,2011.

9.         刘薇。大连市降水中全氟烷酸、羧酸化合物的污染水平和分布特征。大连市自然科学优秀学术论文,一等奖,2011.

10.     金一和,刘薇。中国环境水体和自来水中PFOSPFOA的污染水平和分布特征。辽宁省自然科学学术成果奖 二等奖,2011.

 

指导学生获奖

²  高丽晨.2016年大连理工大学本科毕业设计校优秀论文.

²  杨京亚.第五届格平绿色助学行动--辽宁环境科研教育“123工程”科研课题资助.2014.

²  王玉.“第一届生态毒理学学术研讨会”英国皇家化学会优秀墙报奖.2014.

²  王玉.大连理工大学博士生国际学术会议资助.2013.

²  于明曦.大连理工大学博士生国际学术会议资助.2013.

²  于明曦.第四届格平绿色助学行动--辽宁环境科研教育“123工程”科研课题资助.2013.

²  高倍.持久性有机污染物论坛2013暨第八届持久性有机污染物全国学术研讨会 “安捷伦杯”优秀学术论文奖.2013.

²  高倍.第四届格平绿色助学行动--辽宁环境科研教育“123工程”科研课题资助.2013

²  赵璐璐.国家研究生奖学金.2013.

 

在读学生人数:硕士生:5名;博士生:2(副导师)

毕业学生人数:硕士生:6名;博士生:3(副导师)

                                                   
                                                        最后修改时间:2016-7-17 11:39:58                                                        
                           

版权所有: 大连理工大学 环境学院 © 2010  
地址: 中国 · 辽宁省大连市甘井子区凌工路2号 邮编: 116024 电话: 86-411-84706150 86-411-84708083